Title: A frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity
نویسندگان
چکیده
Frédéric Doussau, Hartmut Schmidt, Kevin Dorgans, Antoine M. Valera, Bernard Poulain, and Philippe Isope. Institut des Neurosciences Cellulaires et Intégratives, CNRS UPR 3212, Université de Strasbourg, 67084 Strasbourg, France Carl-Ludwig Institute for Physiology, University of Leipzig, 04103 Leipzig, Germany Present Address: Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT
منابع مشابه
Frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity
The segregation of the readily releasable pool of synaptic vesicles (RRP) in sub-pools that are differentially poised for exocytosis shapes short-term plasticity. However, the frequency-dependent mobilization of these sub-pools is poorly understood. Using slice recordings and modeling of synaptic activity at cerebellar granule cell to Purkinje cell synapses of mice, we describe two sub-pools in...
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